PROCEDURES FOR THE GMP-COMPLIANT PRODUCTION AND QUALITY CONTROL OF [18F]PSMA-1007: A NEXT GENERATION RADIOFLUORINATED TRACER FOR THE DETECTION OF PROSTATE CANCER

Radiolabeled tracers targeting the prostate-specific membrane antigen (PSMA) have become important radiopharmaceuticals for the PET-imaging of prostate cancer.In this connection, we recently developed the fluorine-18-labelled PSMA-ligand [18F]PSMA-1007 as the next generation radiofluorinated Glu-ureido PSMA inhibitor after [18F]DCFPyL and [18F]DCFB

Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism.Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac.Ceramide generates ceramide-enriched platforms that are involved in receptor clustering within cellular membranes.However, the impact of cell-intrinsic ceramide on

Hand Grip Introduction: Reference laboratory values undergo major changes during pregnancy and if they were defined according to non-pregnant women laboratory reference values, can lead to inappropriate decisions and have adverse effects on pregnancy.Because of the physiological changes in the body of pregnant women, the reference values are not st

BackgroundManagement of infectious waste is essential to address health risks to healthcare workers, patients, and the public.Healthcare facilities, especially in resource-poor settings, however, face significant challenges in effectively and safely handling infectious waste.ObjectiveThis study is aimed to explore the barriers, and facilitators, in

House price is closely associated with the development of the national economy and people’s daily life.Understanding the spatial distribution characteristics and influencing factors of the house price is of great practical significance.Although a lot of attention has been paid to modeling the house price from structure and location attributes, li